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In one study, the infusion of GLP-1 and GIP increased plasma insulin levels by 4.1 and 3.6 times, respectively, compared to a saline infusion in healthy subjects during a hyperglycemic clamp procedure [10]

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AOD-9604 showed a cleaner tolerability profile without the gastrointestinal side effects common with Semaglutide

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[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Ellger B., Richir M.C., van Leeuwen P.A., Debaveye Y., Langouche L., Vanhorebeek I., Teerlink T., Van den Berghe G