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As discussed ( earlier, to the extent the data shows that there would be more than a limited impact on the relative weights initially, which we do not believe will be the case, we intend to provide an opportunity for additional public input and will continue to provide impact analyses of changes in the MS-DRG relative weights in the annual IPPS rulemaking

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Early Phase (Days 1-7) Anti-inflammatory effects may manifest within the first 1-3 days as the peptide begins modulating inflammatory mediators