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However, although the macrocycles immobilized on the SPR sensor chip showed strong binding profiles to the human ectodomain, binding was detected to neither the murine nor the canine ectodomains (Supplementary Table 3 and Supplementary Fig

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The findings of this study allowed the research team of Lau et al to conclude that treatment with cagrilintide in doses ranging from 0.3-4.5 mg resulted in significant dose-dependent weight loss

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Equine CATH-2 only showed antifungal activities at physiological salt concentrations, whereas CATH-3 was only active in low salt medium