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The GLP-1R is expressed on - (glucagon secreting), - (insulin secreting), and - (somatostatin secreting) cells of pancreatic islets, as well as in the heart, lung, kidney, stomach, small intestine, skin, and nerves in the peripheral and central nervous systems (PNS and CNS)

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In the context of disability-related leave, an employer may top off a short-term disability benefit by paying the difference between the disability wage replacement (typically 60% of salary) and the employees full salary

Like other medications in the GLP-1 class, it is administered as a once-weekly injection

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