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Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]

Orlistat (Xenical), one of the medications available both over the counter and by prescription in the form of capsules, targets enzymes in the gut to reduce fat absorption from food