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This finding was further supported when pooled with further observational data 49,50 to a total of 210,521 people with T2DM up to 7.4 years on any GLP-1RA 40

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doi: 10.1016/j.jsbmb.2015.09.029 64 YueLYihuaiHYawenL

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Mechanistically, melatonin alleviated cardiac dysfunction induced by diabetes by upregulating SIRT1-PGC1 to inhibit the expression of Drp1 (Yao et al., 2023)

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