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Consistent with these observations GLP-1R expression in the renal pelvis was augmented in HF
However, these PUFAs are particularly prone to oxidative damage from ROS
Kluck R, Muller S, Jagodzinski C, Hohenfellner K, Buscher A, Kemper MJ, Oh J, Billing H, Thumfart J, Weber LT, Acham-Roschitz B, Arbeiter K, Tonshoff B, Hagenberg M, Kanzelmeyer N, Pavicic L, Haffner D, Zivicnjak M (2022) Body growth, upper arm fat area, and clinical parameters in children with nephropathic cystinosis compared with other pediatric chronic kidney disease entities
During ischemia, dying neurons release massive amounts of glutamate, which overstimulates NMDA receptors on neighboring neurons, causing calcium influx and further cell death