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Enzymatic degradation (pancreatin) Stock solutions of the oligomers were prepared at a concentration of 250 M in DMSO

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Consequently, PF-06882961 is speculated to mirror native GLP-1 more closely by showing partial agonistic activity at recruiting beta-arrestin as well, but hitherto the augmentation of cAMP by the canonical pathway is sufficient to stimulate insulin secretion [45]