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54,55 By doing so, the resulting product has a higher similarity or homology to the amino acid sequence of human GLP-1

c , Heart weights of mice in Extended Data Figs

The mechanisms underlying IGF-1's tendon repair effects involve activation of the IGF-1 receptor on tenocytes and tendon stem cells, leading to enhanced extracellular matrix synthesis, improved cellular migration to injury sites, and optimized remodeling of repair tissue