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Orphanet J Rare Dis 2: 16, 2007 [DOI] [PMC free article] [PubMed] 50.Ghauri FY, McLean AEM, Beales D, Wilson ID, Nicholson JK: Induction of 5-oxoprolinuria in the rat following chronic feeding with N-acetyl 4-aminophenol (paracetamol)

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Antioxidants, including vitamin C, vitamin E, and Coenzyme Q10, play a critical role in protecting cells from oxidative stress (106, 107)

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Alitretinoin, a vitamin A derivative, has shown efficacy in treating hyperkeratotic CHE, with studies reporting significant improvements in Physician Global Assessment (PGA) scores [92]