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They are not equivalent in efficacy but serve different roles in weight management

Furthermore, the regional and temporal variations influence microbial diversity and the hosts response to disease states ( in utero to early and mid-stage adulthood, followed by a progressive collapse of healthy microbiota in late adulthood (Lahiri et al., 2009

A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression

A separate 2025 narrative review by McGuire and colleagues asked a blunter question in its title: "Regeneration or Risk?" [2] Their conclusion: the preclinical evidence is consistently positive, but the absence of human data makes it impossible to generate evidence-based practice guidelines

However, direct stress sensors remain poorly characterized, and most candidates have been identified through indirect genetic and biochemical approaches