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Impaired lipid storage in adipose tissue leads to excess circulating FFAs, which deposit in non-adipose organs such as the liver, heart, and kidneys, driving lipotoxicity and cellular dysfunction

In less pigmented skin, UV exposure is the causative agent, with sun-exposed sites favoured - photodamage in these areas is evident in the form of wrinkles, solar lentigo and actinic keratosis

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Int J Plant Res 2:146150 Elsaied HE, Soliman T, Abu-Taleb HT et al (2019) Phylogenetic characterization of eukaryotic and prokaryotic gut flora of Nile tilapia, Oreochromis niloticus, along niches of Lake Nasser, Egypt, based on rRNA gene high-throughput sequences