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Upon entry into the parenchyma, these cells initiate a secondary immune response, releasing inflammatory mediators such as cytokines, chemokines, proteases, and toxic substances, aggravating myelin and axonal damage [263]

This context-dependent behavior is one of its strengths, but it also means responses may not be entirely predictable

Direct intravenous infusion of macronutrients such as Intralipid and amino acids does not stimulate cortisol secretion (223,224)

Some practitioners offer injections or IV infusions, but these are not yet FDA approved and there is limited evidence of their efficacy

It eliminates the mental arithmetic that trips people up at 6 AM with a syringe in hand