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Durable efficacy of liraglutide in patients with type 2 diabetes and pronounced insulin-associated weight gain: 52-week results from the Effect of Liraglutide on insulin-associated wEight GAiN in patients with Type 2 diabetes (ELEGANT) randomized controlled trial

A second important limitation relates to the substantial heterogeneity observed across studies

Side effects in long term trials Side effects in long term trials Though GLP-1 receptor agonist drugs like Wegovy and Ozempic may seem new to the public, these drugs have been tested in patients for decades

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However, we often recommend checking: Kidney and liver function Thyroid profile Blood glucose and HbA1c Cholesterol levels These provide a useful baseline and ensure your body is responding safely to treatment