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Autophagy as a potential therapeutic target in intervertebral disc degeneration

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However, in other rodents or mammals, selenocysteine cannot be synthesized due to the lack of selenocysteine insertion sequences in related genes, and it is a non-selenium protein replaced by cysteine (Cys) (Brigelius-Floh and Maiorino, 2013)

doi: 10.1089/thy.2012.0548 90 KucharzewskiMBraziewiczJMajewskaUGdS

Common contributors may include: oxidative stress smoking or alcohol excess obesity and metabolic dysfunction heat exposure varicocele genital tract inflammation or infection poor sleep and chronic stress nutritional gaps idiopathic male infertility, where no single obvious cause is found Among these, oxidative stress is one of the most discussed mechanisms