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Summary and Commentary Neurodegenerative disease, especially cognitive loss such as AD, and metabolic disorders that include DM impact a significant portion of the global population, are growing in prevalence with increases in lifespan, and have significant financial consequences for global economies

Dosing plan may include: Dose: 0.5 mg Frequency: Every 3 days (e.g., Monday morning and Thursday evening) Rationale: This gives a total weekly dose of approximately 1.0 mg