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Mechanisms include ATP sensitive K + channel closure, facilitation of VDCCs opening, inhibiting membrane repolarization via Kv channels and Ca 2+ -induced Ca 2+ release from cytoplasmic storage sites 9,10,11,12,13,14

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Results from this study suggest that hepatic fat export in periparturient dairy cows is improved by choline supplementation during the transition period and this may potentially decrease the risk for metabolic disorders in the periparturient dairy cow. [7] Choline is also known to be involved in the synthesis of carnitine, cell membrane phospholipids, and the neurotransmitter acetylcholine