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semaglutide: Key differences Tirzepatide, which is the active ingredient in the brand-name drugs Mounjaro and Zepbound, is classified as a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist, also known as a GIP receptor/GLP-1 receptor agonist

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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically starting at 2.5 mg for 4 weeks, then increasing by 2.5 mg every 4 weeks as tolerated to a maintenance dose of 5, 10, or 15 mg based on individual response

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