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Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies

The trick is to make sure its cooked for a really long time so all of the collagen soaks out of the bones, says Gellman

Every cell in your body produces glutathione, but like collagen, its production naturally decreases with age

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Tirzepatide also slows down the movement of food from the stomach, making you feel fuller for longer