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These doses exceed what a single 1 mL syringe can hold, which means you either need to split the dose across two injections or move to a 20 mg/mL concentration

Donaldson, Metabolic vitamin B 12 status on a mostly raw vegan diet with follow-up using tablets, nutritional yeast, or probiotic supplements , Annals of Nutrition & Metabolism , vol

Following the remodelling phase, a higher proportion of synthesised type I collagen, a corresponding decrease in cellularity, glycosaminoglycan content and type III collagen (Sharma and Maffulli 2005) can be observed

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A typical protocol is once-a-month injections of vitamin B12 for 3-4 times