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Infiltrating cells in the CNS interact with pathologically deposited -synuclein molecules, which activate pattern-recognition receptors (TLR2, TLR4) on monocytes and microglia, increasing NF-B activation and inflammasome signaling (NLRP3) [127]
Oral glutathione is effective but has lower bioavailability compared to IV methods
Cook GC, Sherlock S
6 Discussion This review provides a comprehensive overview of the regulatory effects of flavonoids on immune cell functions and their strategic applications in the management of inflammatory disorders ( Figures 1 and 2 )
Data are shown as mean S.D (n = 2)
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