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To the extent viscosity considerations potentially limit the use of a syringe/needle delivery system, thermoreversible gels or post-administration viscosity-enhancing options are also envisioned, as well as alternative delivery systems, including pumps, microinjection devices and the like

doi: 10.1158/0008-5472.CAN-05-3796 166

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RESULTS Impaired glucose and/or lipid metabolism, a sign of obesity and T2DM [6], increases hepatic gluconeogenesis and inhibits the peripheral utilization of glucose, which eventually could lead to insulin resistance [19]

doi: 10.1097/MD.0000000000022253 18