In reality, long-term retatrutide management involves three distinct phases, each requiring different clinical attention
What has become increasingly clear since 2023 is that GLP-1 receptors are also active in areas of the brain involved in reward, impulse control, motivation, and stress regulation
These injectable medications work by mimicking natural hormones that regulate appetite and blood sugar levels
Patients with pre-existing cardiovascular disease, chronic kidney disease, or those taking multiple medications should maintain closer communication with their healthcare team
Beyond addressing supply issues, the approach could potentially reduce costs for these expensive medications, which can run patients thousands of dollars annually without insurance coverage