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Intranasal administration, though less studied with Dihexa specifically, would theoretically provide the most direct CNS delivery with minimal systemic exposurepotentially requiring even less frequent dosing to maintain effective brain tissue concentrations

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Near-infrared fluorophore IR-61 improves the quality of oocytes in aged mice via mitochondrial protection

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

The results highlight why one might deliver different results than the other