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This study demonstrates that p53-specific effects of APR-246 are only observable in a narrow dosing window, under a specific set of conditions

Future work should prioritize delivery platforms that localize exposure to pelvic lesions, including intraperitoneal or intralesional depots and nanocarriers, alongside triggerable or receptor-guided prodrugs designed to activate within the biochemical milieu of lesions

This includes screening, supervision and post-infusion observation, all of which contribute to pricing

Crop Sci 25(6):944949 Cyr AR, Domann FE (2011) The redox basis of epigenetic modifications: from mechanisms to functional consequences

Rights and permissions About this article Cite this article Chauhan, A., Audhya, T