The most common side effects include infection, headache, feeling weak, nausea, swelling of your tongue, runny nose, tingling of the hands and feet
excess is excreted in urine, often causing bright yellow coloration, and no upper toxicity level has been observed)
The folate-cobalamin interaction is pivotal for normal synthesis of purines and pyrimidines and the transfer of the methyl group to cobalamin is essential for the adequate supply of tetrahydrofolate, the substrate for metabolic steps that require folate
Refrigerate opened vials at 28C, mark the 28-day discard date, and treat temperature excursions as protocol failures
The MHRA advises checking B12 levels in patients on metformin who have symptoms of deficiency or risk factors, and considering periodic monitoring