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It had been reported that the accumulation of cytoplasmic double-stranded DNA (dsDNA) and the expression level of cGAS were positively correlated with the severity of synovitis in RA patients [22]

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There are simple, practical ways to manage feeling cold while continuing Wegovy safely: Eat regular, balanced meals Include enough protein and iron-rich foods Stay well hydrated Dress in layers and keep warm indoors Avoid skipping meals unnecessarily Never change your dose without medical advice These steps help support energy balance and reduce cold sensitivity