Fourth, there were more unscheduled follow-ups with semaglutide compared to placebo, which may have affected the results because of the increase of healthcare or research personnel contact
Glycemic category (normoglycemia, prediabetes or type 2 diabetes) was determined by investigators on the basis of available information (for example, medical records, concomitant medication, and blood glucose variables) and in accordance with American Diabetes Association criteria 30 , which for prediabetes includes fasting plasma glucose levels of 100 mg dl 1 (5.6 mmol l 1 ) to 125 mg dl 1 (6.9 mmol l 1 ) or HbA 1c levels of 5.76.4% (3947 mmol l 1 ), and for type 2 diabetes includes fasting plasma glucose levels of 126 mg dl 1 (7.0 mmol l 1 ) or HbA 1c levels 6.5% (48 mmol l 1 )
The drug is available in injection form and is usually administered once per week
Medical and Editorial Standards Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims
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