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Glutathione functions primarily through its thiol group on the cysteine residue, which serves as an electron donor for neutralizing reactive oxygen species (ROS) and reactive nitrogen species (RNS)

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The treatment effect was due to a significant reduction in the risk of hospitalization for heart failure in subjects randomized to dapagliflozin 10 mg [HR 0.73 (95% CI 0.61, 0.88)], with no change in the risk of CV death (Table 18 and Figures 4 and 5)

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