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Copper Dyshomeostasis and brain disorders Chronic copper intoxication causes region-specific copper accumulation in the CNS of male Wistar rats, following intra-peritoneal injections of copper lactate (0.15 mg Cu/100 g body weight) daily for 90 days

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For SGLT2 inhibitor users, the cumulative incidence of treatment discontinuation was 27.9% (95% CI 27.6, 28.1) at 1 year and 45.9% (95% CI 45.5, 46.2) at 3 years, when using a grace period of 90 days