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For instance, in the presence of the antibiotic metronidazole, thiaminase I substitutes the thiazolium ring of thiamine with the imidazolium ring of metronidazole, resulting in a thiamine antagonist which can inhibit TPK (160)

While these options may not offer permanent remission like Accutane, they can provide significant improvement, especially when used as combination therapy to address the underlying causes of the acne

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Discussion TPE has been shown to improve many signs of aging-related cognitive decline