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Nausea usually peaks during days 37 after your first injection and improves substantially by week 34

Patients who stop the medication typically see weight return over time, which is consistent with the clinical understanding that these medications address biological drivers of appetite rather than "curing" the underlying condition

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Berberine can lower blood glucose and blood pressure, meaning it may potentiate the effects of antidiabetic medications (such as metformin or insulin) and antihypertensives, increasing the risk of hypoglycaemia or hypotension

Gastrointestinal emergencies: evidence-based answers to key clinical questions