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We suggest that reduced GPx1 in monocytes recruited to the gut and intestinal macrophages renders these cells vulnerable to reactive oxygen species-evoked ferroptosis cell death and that unraveling the participation of this pathway in Crohns disease may reveal novel therapeutic approaches to this chronic condition

Egan JM, Montrose Rafizadeh C, Wang Y, Bernier M, R J

The movement of mGs coincided with the localization of GLP-1R as evidenced by BRET and confocal microscopy demonstrating time-dependent receptor trafficking from the plasma membrane to early endosomes and the Golgi apparatus following agonist stimulation (Supplementary Figs

The NHS recognises that psychological wellbeing is integral to sexual health, and these factors often coexist with chronic disease