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Constipation is another common issue, reported in 21-25% of retatrutide users and a significant percentage of cagrilintide users

We propose a 4A conceptual frameworkAccessibility, Agility, Awareness, and Adaptability to accelerate therapeutic development and expand access to care for these underserved rare disease populations

[1] [2] It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

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