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The Cureus/PMC study documented both allodynia and dysesthesia in semaglutide and tirzepatide users, suggesting they may represent different points on the same mechanistic spectrum

Cellular mechanisms underlying the antidepressant effects of ketamine: role of -amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors

Paraskevas LR, Halpern AC, Marghoob AA

150 Azurophil granules possess potent bactericidal activity, harboring a range of antimicrobial components including bactericidal/permeability-increasing protein, myeloperoxidase (MPO), defensins, cathepsin G, lysozyme, and proteinase 3

Including circadian rhythm markers such as dim light melatonin onset would strengthen the informative value of these trials, where feasible