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This is why the STEP trial protocol includes two intermediate doses (1.7 mg) before reaching 2.4 mg, and why many people find their sweet spot below maximum

Do not use expired or discolored injections

An anecdotal clinical observation is that traumatic causes of subungual bleeding are associated with a proximal white transverse band in many instances [33]

Reach out to your doctor if you notice any of the following: skin sensitivity that gets worse instead of better after two to three weeks, widespread rash or visible irritation that spreads beyond the injection area, blistering or peeling skin, or any signs of a serious allergic reaction like facial swelling, difficulty breathing, or a rapid heartbeat

Such dosing recommendations are for research use only