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For example, Icarin was confirmed to inhibit ECM degradation and ferroptosis in chondrocytes, thereby alleviating articular cartilage damage in OA rats by restoring SLC7A11 and GPX4 expression (Xiao et al., 2024)

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In D-galactose-induced aging rats, L-theanine could protect the liver not only by reducing the levels of pro-inflammatory factors, such as IL-1, TNF-, and IL-6 but also by efficiently reducing the production of edema and vacuole induced by D-galactose (88)

As se puede ajustar el plan de tratamiento a tiempo y evitar complicaciones serias

Consequently, a crucial task will be to select the more active agents and integrate them effectively in well-designed clinical trials incorporating predictive biomarkers such as gene mutations, amplifications, and immunohistochemical c-MET overexpression