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Mice were subsequently divided into 4 groups as follows: mice that continued receiving chow diet for 2 additional weeks (C), mice fed a chow diet and subcutaneously (s.c.) injected Fc-GLP-1 (GLP-1(736)NH2 sequence HGEGT FTSDV SSYLE GQAAK EFIAW LVKGG-Fc at 10 nmol/kg every two days (C + Fc-GLP-1), mice that continued with MCD diet (MCD) and mice fed a MCD diet and injected Fc-GLP-1 (M + Fc-GLP-1)

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The pivotal trials that led to Wegovy's approval (the STEP programme) included diverse patient populations but did not specifically analyse outcomes in participants with ADHD

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Peak GH concentrations occurred 30-40 minutes post-subcutaneous injection, with GH effects persisting 2-3 hours