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Reports of sleep disorders were typically characterized as insomnia and occurred in 8.1% and 11% of patients treated with phentermine and topiramate extended-release 7.5 mg/46 mg and 15 mg/92 mg, respectively, compared to 5.8% of patients treated with placebo

Adding a Second Medication: What Works Best When a patient plateaus on a single GLP-1 medication, the clinical response is to increase the dose of that medicationnot to introduce a second one

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