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CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway
Moreover, CXCL12 and CCL5 play an important role in immune cell recruitment in affected skin, and serum CXCL12 levels are associated with disease activity.23 Additionally, oxidative stress induces the secretion of chemokines like CXCL16.24 Other cytokines elevated in vitiligo include IL-1, IL-2, IL-17, IL-22, IL-23, and IL-33
A report from the EMAs PRAC, published on 12 April 2024, said: After reviewing the available evidence from non-clinical studies, clinical trials, post-marketing surveillance data and the available studies the PRAC considers that no update to the product information is warranted. The PRAC statement said that market authorisation holders would continue to monitor events, including new studies, as part of their pharmacovigilance activities