Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo , effectively reducing oxidative stress, apoptosis , and ferroptosis in hair cells
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Medications Statins (first-line) Ezetimibe, PCSK9 inhibitors Fibrates (for triglycerides) LDL = main target for cardiovascular risk reduction HDL protective, total cholesterol alone is less informative Familial hypercholesterolemia early CAD, tendon xanthomas Cholesterol is a lipid essential for cell membranes, steroid hormones, and bile acids, with LDL increasing cardiovascular risk and HDL being protective To view or add a comment, sign in Insulin: The Master Regulator of Whole-Body Metabolism Insulin is often simplified as a blood glucose In reality, insulin functions as a central metabolic signal that coordinates energy balance, nutrient partitioning, vascular health, immune activity, and inter-organ communication
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PMID: 41468591
