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however, current evidence remains insufficient to support a direct antitumor effect of GCGR activation alone

1-3 Molecular Structure Sequence: HXEGTFTSDVSSYLEGQAAK-OH.steric diacid-EFIAWLVRGRG Molecular Formula: CHNO Molecular Weight: 4113.58 g/mol PubChem CID: 56843331 CAS Number: 910463-68-2 Synonyms: NN9535

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In turn, zinc positively modulates the de novo synthesis of GSH through induction of Nrf2 transcription factor, which is responsible for the upregulation of the gene coding for the rate-limiting enzyme of GSH synthesis, glutamate cysteine ligase (GCL) (211)

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