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Proactive hydration, electrolytes, sleep regularity, and a preplanned training schedule mitigate risk

Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection

Upon activation by GLP-1RAs, GLP-1R initiates diverse intracellular cascades, such as the cyclic adenosine monophosphate (cAMP) / protein kinase A (PKA) pathway and phosphatidylinositol 3-kinase (PI3K) / protein kinase B (Akt) signaling pathway [1, 9]

Pediatr Drugs 28 , 239248 (2026)

Finally, a pooled analysis of RCTs and open-label phase III studies showed that once-weekly exenatide reduced albuminuria 26% (95% CI%: 39.5 to 10%) compared with comparators (Van Der Aart-Van Der Beek et al., 2020)