Based on what we know today, clinically significant exposure through breast milk appears unlikely
Cells were lysed in 1 mL ChIP lysis buffer (50 mmol/L HEPES-KOH, pH 7.5, 140 mmol/L NaCl, 1 mmol/L EDTA, pH 8.0, 1% Triton X-100, and 0.1% deoxycholate with 0.1 mmol/L PMSF and the EDTA-free protease inhibitor cocktail)
An initial regimen of a medium-strength (class III) topical corticosteroid such a triamcinolone acetonide 0.1% applied daily to lesional skin can be tried, especially on areas off the face
It helps to inhibit melanin production, which can lead to significant skin brightening and a reduction in hyperpigmentation, while regular treatment can improve overall skin texture as well
This includes a complete metabolic panel, fasting insulin, HbA1c, fasting glucose, lipid panel (complete with LDL particle count if available), IGF-1, growth hormone levels (random and stimulated if possible), liver enzymes (ALT, AST, GGT), kidney function markers (creatinine, BUN, eGFR), complete blood count, and thyroid panel
