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Semaglutide requires **4 injections per month** compared to approximately **30 injections per month** for AOD-9604

Moreover, the resting heart rate variability (HRV) parameters also differed in ME/CFS patients, with a higher low frequency power of HRV (LFP) and a lower high frequency power of HRV (HFP)

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Injections provide a direct, efficient way to replenish B12 stores without relying on oral supplements, which may be less effective for some people