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Interestingly, avoidance learning-an anxiety response-appears to depend on pkc activity as well, as it can be blocked by immediate polymixin B, a pkc and calcium/calmodulin-dependent kinase II inhibitor, applied to rat amygdala (Walker and Gold, 1994)

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In the setting of tissue protection by PUFA, experimental studies in rats by Videla and colleagues showed that the combination of DHA plus thyroid hormone (T3) protects from liver injury through a synergistic action that also involves causing increased intrahepatic levels of resolvins (116120)