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Endocrinologists also closely monitor heart rate because there is a theoretical risk of a transient, mild elevation or low-grade arrhythmias with triple agonists, as glucagon receptors are also expressed in the heart

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One Cochrane review found that high-dose oral vitamin B12 supplements (1,000 mcg to 2,000 mcg per day) was as effective for correcting megaloblastic anemia as B12 shots

While vitamin B12 deficiency is more common in certain populations, it is generally preventable and treatable with dietary changes, supplements, consuming fortified plant-based foods (especially important for vegans) or injections of vitamin B12

Like they're looking at very specific mechanisms and they're probably doing dosing that is different than what you would be taking