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An increased susceptibility to sepsis-induced ARDS and lethality 34 was observed in mice lacking the transcription factor Nrf2, which has among its target genes the GSH biosynthetic enzyme gamma-glutamylcysteine synthase
Dietary Modifications Foods to AVOID (especially during dose escalation): High-fat meals (fried foods, heavy creams, fatty meats) Very spicy foods Large portions Carbonated beverages (can worsen bloating) Alcohol (increases nausea risk) Foods that HELP: Bland carbohydrates: crackers, toast, rice Ginger: tea, candied ginger, ginger ale (real ginger) Small, frequent meals (56 mini-meals vs 3 large) Protein-rich foods: chicken, fish, eggs (smaller portions) Cold foods (less smell = less nausea trigger) 3
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Plum A, Jensen LB, Kristensen JB
Regeneron stated that no causal relationship has been established between the deaths and the investigational treatments
