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The coordination of mucin production and secretion with ion and water homeostasis is discussed to evaluate how changes in sodium, calcium, bicarbonate, and chloride are responsible for failures of mucin unfolding and the subsequent biophysical properties of the mucus

Poster Session I - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.06 - IMAGING - Hyperacute P084 - ESOC25-2281 ASSESSING THE AGREEMENT BETWEEN AUTOMATED AND NEURORADIOLOGIST-DERIVED ASPECTS SCORES IN ACUTE STROKE IMAGING Allam Harfoush 1,2 , Lakshmi Saranya 1 , Fathalla Elnagi 3 , Kumar Pulapula 1 , Anastasia Liaretidou 3 , Parthasarathy Karunakaran 1 , Ciprian Rusu 3 , Patricia O'keefe 1 , Kausik Chatterjee 1,2 1 Countess of Chester Hospital, Chester, United Kingdom, 2 The University of Chester, Chester, United Kingdom, 3 St Helens and Knowsley Teaching Hospitals NHS Trust, St Helens and Knowsley, United Kingdom Background and Aims: The Alberta Stroke Programme Early CT Score (ASPECTS) is widely used to identify early ischaemic changes in acute stroke

Others advise against it due to limited safety data on the combination

It is used in research on energy metabolism and, in certain specific clinical contexts, under professional indication and supervision

however, it does not prevent reinfection and the emergence of drug resistance is a concern