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Axitinib decreases the disruption of tight junction proteins and reduces permeability of the BBB in AD disease mice while also increasing spatial awareness, exploration, associative memory, working memory and lowered amyloid-beta, indicating the potential for this drug to slow disease pathology [136]

Amino acids V12 (putative oxyanion hole), F112 (active site architecture), N108 (flavonoid binding) and C13 (GSH stabilization) were fully randomized by site saturation mutagenesis (NNK codons), and the created Pt GSTF8 variants were tested for conversion of flavan-3,3,4-triol ( 4 ) to cyanidin ( 8 ), and for their GSH-transferase activity towards CDNB ( 5 ) as a control of catalytic competence

Hydrogen peroxide induced oxidative damage on mechanical properties of the articular cartilage 2017

OPMD, oral potentially malignant disorders

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